The San Francisco 49ers might not start the 2022 season with all of their players available.

The NFC West team plays the Bears in Chicago to open the 2022 season.

Trey Lance will be making his season debut. 

Unfortunately, it looks like one of the 49ers' best offensive weapons won't be on the field.

In Week 1, against the Bears, George Kittle is "not expected" to play.

George Kittle is being treated for groyne pain. It's not thought to be a major issue.

However, the 49ers won't be taking any chances. The season is lengthy.

In the regular season's opening game against the Bears on Sunday afternoon, Lance will have to rely on Deebo Samuel and Brandon Aiyuk.

George Krieger Kittle plays tight end for the National Football League's San Francisco 49ers.

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