The Buffalo Bills humiliated the reigning champion Los Angeles Rams in the 2022 NFL season opening on Thursday night, and now they have to cope with some bad injury news.

Kyren Williams, a rookie running back for the Rams, suffered a high ankle sprain during the first quarter of Thursday night's defeat. 

The head coach Sean McVay said on Friday that Williams would undergo surgery. 

Williams is predicted to miss six to eight weeks of action.

This information follows Cam Akers three touches on Sunday night, during which he gained zero yards.

With 73 yards gained from 18 touches, Darrell Henderson served as Los Angeles' starting running back (13 carries, five receptions).

Williams, 22, who was chosen by the Rams in the fifth round of the 2022 NFL Draft out of Notre Dame, was third on the depth chart at running back going into the season.

And with Akers, who has suffered from a torn Achilles and most recently a soft-tissue ailment, McVay doesn't seem to have much faith in him right now.

Williams might have soon had a significant role in the Rams' attack.

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