49ers' Aiyuk Inactive vs. Giants Due to Shoulder Injury

San Francisco 49ers wide receiver Brandon Aiyuk is sidelined for Thursday's game against the New York Giants due to a shoulder injury.

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Aiyuk had been questionable for the matchup, but his shoulder injury has rendered him inactive.

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In response, the 49ers have elevated receiver Chris Conley from the practice squad for the game.

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Aiyuk sustained the injury during the previous Sunday's game against the Los Angeles Rams, where he managed three catches for 43 yards.

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Aiyuk has been a standout performer this season, leading the 49ers with 172 receiving yards and two touchdowns in two games, tying with Deebo Samuel for receptions.

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He earned NFC Offensive Player of the Week honors after an outstanding Week 1 performance with eight receptions, 129 yards, and two touchdowns against the Pittsburgh Steelers.

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The 49ers, now back at home for Week 3, will be without Aiyuk and cornerback Ambry Thomas, who also suffered an injury during the Rams game.

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GM Lynch had previously indicated that both players game-time decisions, listed as questionable due to short turnaround for Thursday night game.

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